发明名称 |
Non-irritating benzoyl peroxide |
摘要 |
A method of making crystalline benzoyl peroxide particles having a particle size no greater than 25 microns and formed by wet milling in the absence of solvents and wherein the crystalline benzoyl peroxide is not irritating to the skin. A method of making a therapeutic or cosmetic composition comprising a water-based gel containing the crystalline benzoyl peroxide. |
申请公布号 |
US9072675(B2) |
申请公布日期 |
2015.07.07 |
申请号 |
US201414178460 |
申请日期 |
2014.02.12 |
申请人 |
Essential Ingredients, Inc. |
发明人 |
Gerlach Chris;Davies Mike;Dawes Stephen M. |
分类号 |
A61K8/38;A61K8/04;A61K9/14;A61K9/06;A61K9/00;C07C407/00;C07C409/34;A61Q19/00 |
主分类号 |
A61K8/38 |
代理机构 |
Banner & Witcoff, Ltd. |
代理人 |
Banner & Witcoff, Ltd. |
主权项 |
1. A method of preparing crystalline, solvent-free, benzoyl peroxide particles comprising:
adding water to solid benzoyl peroxide; milling to break up agglomerates and form an aqueous benzoyl peroxide composition; adding a dispersion system and mixing; adjusting the pH to 2.8 to 6.6; and milling to a particle size not more than 25 microns. |
地址 |
Lawrenceville GA US |