发明名称 |
C-reactive protein imprinted polymer film and microchip system utilizing the same |
摘要 |
The present invention is a C-reactive protein imprinted polymer film. The C-reactive protein antibody imprinted polymer film comprises a plurality of imprinted nanocavities with unified orientation and distribution formed by removing a plurality of C-reactive proteins from a polymer film. Its ability to capture the target proteins can achieve 99% compared with the natural antibodies. The present invention further provides a C-reactive protein microchip system formed by the dynamic capacitance sensing method with the above imprinted polymer film. The C-reactive protein microchip system comprises a body having a first chamber and a second chamber, and a detector. |
申请公布号 |
US9075054(B2) |
申请公布日期 |
2015.07.07 |
申请号 |
US201213715693 |
申请日期 |
2012.12.14 |
申请人 |
MACKAY MEMORIAL HOSPITAL;NATIONAL TSING HUA UNIVERSITY |
发明人 |
Hong Chien-Chong;Chen Szu-Ying;Horng Jia-Cherng;Chen Chie-Pein |
分类号 |
G01N15/06;G01N33/00;G01N33/48;G01N33/545 |
主分类号 |
G01N15/06 |
代理机构 |
WPAT, P.C. |
代理人 |
WPAT, P.C. ;King Anthony |
主权项 |
1. A C-reactive protein imprinted polymer film, comprising:
a plurality of imprinted nanocavities with unified orientation and distribution formed by removing a plurality of C-reactive proteins from a polymer film, wherein the C-reactive proteins are bound to a plurality of antibodies on a modified surface of a first substrate. |
地址 |
Taipei TW |