发明名称 |
Anti-cancer compound and pharmaceutical composition containing the same |
摘要 |
The invention relates to a compound of formula (I), more specifically in the levorotatory form (1a) thereof, in particular the form having a rotatory power [α]D=−38.6+0.7 at a concentration of 0.698 mg/ml in methanol. The compound may be in the form of a base or an acid addition salt, in particular a pharmaceutically acceptable acid. The compound is a selective Aurora A and B kinase inhibitor and can be used as an anticancer drug.; |
申请公布号 |
US9073917(B2) |
申请公布日期 |
2015.07.07 |
申请号 |
US201013320965 |
申请日期 |
2010.05.17 |
申请人 |
SANOFI |
发明人 |
Carry Jean-Christophe;Cheve Michel;Clerc Francois;Combeau Cecile;Gontier Sylvie;Krick Alain;Lachaud Sylvette;Schio Laurent |
分类号 |
A61K31/4745;A61P35/00;C07D405/12;C07D471/04;C07D235/26 |
主分类号 |
A61K31/4745 |
代理机构 |
Morrison & Foerster LLP |
代理人 |
Morrison & Foerster LLP |
主权项 |
1. A compound of formula (I): |
地址 |
Paris FR |