Cyclic sulfonium salt, process for production of same, and α-glucosidase inhibitor comprising same

摘要

Provided is a novel cyclic sulfonium salt compound which is useful for the prevention or treatment of diabetes and the like. The present invention relates to a novel cyclic sulfonium salt compound represented by general formula (I) or (II), an isomer or solvate of the compound, or a pharmaceutically acceptable salt of the compound or the isomer or solvate. The present invention also relates to an α-glucosidase inhibitor, a pharmaceutical composition for preventing or treating diabetes, and an anti-diabetes food, each of which comprises the compound represented by general formula (I) or (II) and the like.

主权项

1. A cyclic sulfonium salt compound as represented by general formula (I):wherein
R1 is hydrogen atom or —(CH(OH))n-CH2OH (wherein n is 0 or an integer of 1 or 2); R2 is a benzyl group, an o- , m-, or p-halobenzyl group, an o-, m-, or p-nitrobenzyl group, an o-, m-, or p-methylbenzyl group, an o-, m-, or p-trifluoromethylbenzyl group, a hydroxymethylbenzyl group, a naphthylmethyl group, or a pyridylmethyl group and X− is a conjugated basic ion of halogen or BF4 or an isomer or a solvate thereof or a pharmaceutically acceptable salt thereof.