发明名称 |
Volumetric deformable registration method for thoracic 4-D computed tomography images and method of determining regional lung function |
摘要 |
A method of deformable image registration for thoracic 4-D computed tomography (CT) images includes: receiving, by a processing device, a set of thoracic 4-D CT images; and iteratively solving, by the processing device, an energy function applied to subsequent images of the set of thoracic 4-D CT images to transform the subsequent images into respective optical flow fields between the subsequent images, the energy function enforcing the following constraints on the subsequent images: intensity constancy; mass conservation; gradient constancy; and spatio-temporal smoothness. A method of determining regional lung function includes: receiving, by a processing device, a set of thoracic 4-D CT images of a lung; transforming, by the processing device, the set of 4-D CT images of the lung into respective spatial voxel-wise deformation maps; and transforming, by the processing device, the spatial voxel-wise deformation maps into respective spatial voxel-wise strain maps of the lung indicating regional mechanics of the lung. |
申请公布号 |
US9076201(B1) |
申请公布日期 |
2015.07.07 |
申请号 |
US201313854729 |
申请日期 |
2013.04.01 |
申请人 |
University of Louisville Research Foundation, Inc. |
发明人 |
Negahdar Mohammadrreza;Amini Amir A.;Dunlap Neal;Woo Shiao |
分类号 |
G06T7/00 |
主分类号 |
G06T7/00 |
代理机构 |
Stites & Harbison PLLC |
代理人 |
Stites & Harbison PLLC ;Haeberlin Jeffrey A.;Wright Terry L. |
主权项 |
1. A method of deformable image registration for thoracic 4-D computed tomography (CT) images, comprising:
receiving, by a processing device, a set of thoracic 4-D CT images; and iteratively solving, by the processing device, an energy function applied to subsequent images of the set of thoracic 4-D CT images to transform the subsequent images into respective optical flow fields between the subsequent images, the energy function enforcing the following constraints on the subsequent images:
intensity constancy;mass conservation;gradient constancy; andspatio-temporal smoothness. |
地址 |
Louisville KY US |