Small molecule trail gene induction by normal and tumor cells as an anticancer therapy

摘要

Methods and compositions relating to TIC10 are described according to aspects of the present invention. The compositions and methods have utility in treating disease, particularly cancer in a subject in need thereof, including a human subject as well as subjects of other species. The compositions have utility in treating brain cancer in a subject in need thereof.

主权项

1. A method of treatment of a subject having cancer, comprising:
administering to the subject a pharmaceutical composition comprising a pharmaceutically effective amount of: (I) or a pharmaceutically acceptable salt, hydrate, or solvate thereof, wherein the cancer is selected from the group consisting of colon cancer, breast cancer, lymphoma, and non-small cell lung cancer.