Automatic delivery device with triggering mechanism

摘要

The present patent application relates to delivery devices, methods, and systems of delivering at least one medicament from a reservoir using an automatic delivery device. Such an automatic delivery device system may comprise a dose injecting mechanism and a dispense interface, such as a needle module. The dose injecting mechanism comprises a triggering mechanism. An activating member, such as a needle guard of the needle module, can be used to initiate the triggering mechanism to enable the device to administer the set dose. The single dispense interface may comprise a medicated module containing at least one dose of a secondary medicament. The dose injecting mechanism may comprise a dose setting mechanism.

主权项

1. A drug delivery system to administer one or more medicaments operable through a delivery device and a dispense interface in the form of a medicated module, the delivery device comprising,
a housing defining a primary reservoir, the primary reservoir containing a first medicament; a dose injecting mechanism operably connected to the primary reservoir containing the first medicament containing at least one drug agent; a triggering mechanism operably configured to the dose injecting mechanism of the delivery device; an outlet configured for fluid communication with the primary reservoir; wherein the medicated module is attachable to the drug delivery device, the medicated module comprising: an outer housing having an inner surface, a proximal end and a distal end, where the proximal end has an upper hub holding a first double-ended needle cannula and a connector configured for attachment to a delivery device; a bypass housing having an outer surface and slidably engaged with an upper radial stand off on the inner surface of the outer housing; a secondary reservoir within the bypass housing comprising at least a single dose of a secondary medicament; an activating member in the form of a guard, the guard having an internal proximal face and a drive tooth on an inner surface, where the drive tooth is slidably engaged with a track on the outer surface of the bypass housing; a lower hub slidably engaged with the outer surface of the bypass housing and slidably engaged with the inner surface of the guard holding a second double-ended needle cannula; and a first biasing member engaged between the internal proximal face of the guard and with the lower hub, wherein during a dose administration step, when the guard is caused to be moved in a proximal direction, the guard acts on the triggering mechanism so as to allow the dose injecting mechanism to cause the first medicament from the primary reservoir and the secondary medicament from the secondary reservoir to be expelled through the dispense interface, and allows the second double-ended needle cannula to reach a given penetration depth before the guard activates the triggering mechanism.