发明名称 Glucagon receptor modulators
摘要 The present invention provides a compound of Formula (I); or a pharmaceutically acceptable salt thereof wherein R1, R2, R3, A1, A2, A3, A4, L, B1, B2, B3 and B4 are as defined herein. The compounds of Formula I have been found to act as glucagon antagonists or inverse agonists. Consequently, the compounds of Formula I and the pharmaceutical compositions thereof are useful for the treatment of diseases, disorders, or conditions mediated by glucagon.
申请公布号 US9073871(B2) 申请公布日期 2015.07.07
申请号 US201414471576 申请日期 2014.08.28
申请人 Pfizer Inc. 发明人 Aspnes Gary Erik;Didiuk Mary Theresa;Filipski Kevin James;Guzman-Perez Angel;Lee Esther Cheng Yin;Pfefferkorn Jeffrey Allen;Stevens Benjamin Dawson;Tu Meihua Mike
分类号 A61K31/415;C07D231/12;C07D207/34;C07D231/14;C07D231/16;C07D231/18;C07D231/54;C07D231/56;C07D233/61;C07D233/64;C07D233/68;C07D233/70;C07D233/84;C07D249/06;C07D249/08;C07D261/08;C07D401/04;C07D401/12;C07D401/14;C07D403/04;C07D405/14;C07D487/04;C07D403/12 主分类号 A61K31/415
代理机构 代理人 Wasicak James T.
主权项 1. A compound of structure
地址 New York NY US