Process for obtaining non-allergic propolis

摘要

The present disclosure relates to a process for pre-treating raw propolis comprising at least one allergenic activity substance, which comprises reacting propolis with a probiotic microorganism containing one or more cinnamoyl-esterase activity enzymes to obtain a semisolid propolis derivative substantially without or impoverished of allergenic substances. The present invention also relates to a method of purifying semisolid propolis derivative to obtain a hydroalcoholic hydrodispersible propolis derivative.

主权项

1. A process for pre-treating propolis comprising at least one allergenic substance of general formula (1) wherein R is an alkyl or alkenyl selected from the group comprising 3-methyl-2-butenyl, 2-methyl-2-butenyl, 3-methyl-3-butenyl, benzyl and phenylethyl, wherein raw propolis is caused to react at a temperature of 37° C.±2° C. with a microorganism comprising at least one enzyme having cinnamoyl-esterase activity to obtain a semisolid propolis derivative with a reduced content of allergenic substances.