发明名称 |
SINGLE NUCLEOTIDE POLYMORPHISMS USEFUL TO PREDICT CLINICAL RESPONSE FOR GLATIRAMER ACETATE. |
摘要 |
<p>Provided is a method for treating a human subject afflicted with multiple sclerosis or a single clinical attack consistent with multiple sclerosis with a phanmaceutical composition comprising glatiramer acetate and a pharmaceutically acceptable carrier, comprising the step of detenriining the genotype of the subject at one or more single nucleotide polymorphisms (SNPs), identifying the subject as a predicted responder or non-responder to glatiramer acetate based on the determined SNP genotype, and administering the pharmaceutical composition comprising glatiramer acetate and a pharmaceutically acceptable carrier to the subject only if the subject is identified as a predicted responder to glatiramer acetate.</p> |
申请公布号 |
MX2014004309(A) |
申请公布日期 |
2015.07.06 |
申请号 |
MX20140004309 |
申请日期 |
2012.10.09 |
申请人 |
TEVA PHARMACEUTICAL INDUSTRIES LTD. |
发明人 |
AMIR, TCHELET;FABIO, MACCIARDI;JOSEPH, LEVY |
分类号 |
C12Q1/68;A01N37/12 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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