发明名称 |
TRICYCLIC NUCLEOSIDES AND OLIGOMERIC COMPOUNDS PREPARED THEREFROM |
摘要 |
The present invention provides novel tricyclic nucleosides and oligomeric compounds prepared therefrom. Incorporation of one or more of the tricyclic nucleosides into an oligomeric compound is expected to enhance one or more properties of the oligomeric compound. Such oligomeric compounds can also be included in double stranded compositions. In certain embodiments the oligomeric compounds provided herein are expected to hybridize to a portion of a target RNA resulting in loss of normal function of the target RNA. |
申请公布号 |
IN1838MUN2014(A) |
申请公布日期 |
2015.07.03 |
申请号 |
IN2014MUMNP1838 |
申请日期 |
2014.09.18 |
申请人 |
UNIVERSITÄT BERN |
发明人 |
LEUMANN CHRISTIAN;DUGOVICH BRANISLAV;LIÉTARD JORY |
分类号 |
C07H19/06;C07H21/00 |
主分类号 |
C07H19/06 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|