发明名称 TRIFLUOROMETHYL PYRAZOLYL GUANIDINE F1F0-ATPASE INHIBITORS AND THERAPEUTIC USES THEREOF
摘要 The invention provides trifluoromethyl pyrazolyl guanidine compounds that inhibit F1F0-ATPase, and methods of using trifluoromethyl pyrazolyl guanidine compounds as therapeutic agents to treat medical disorders, such as an immune disorder, inflammatory condition, or cancer.
申请公布号 US2015183745(A1) 申请公布日期 2015.07.02
申请号 US201414565463 申请日期 2014.12.10
申请人 Lycera Corporation 发明人 Hurd Alexander R.;Taylor Clarke B.;Wang Jian;Zhou Peng
分类号 C07D231/38 主分类号 C07D231/38
代理机构 代理人
主权项 1. A compound represented by Formula I: or a geometric isomer or tautomer; or a pharmaceutically acceptable salt or solvate of any of the foregoing; wherein R1 is a chloro group located at either the meta-position or para-position of the phenyl group to which it is attached.
地址 Ann Arbor MI US