发明名称 |
TRIFLUOROMETHYL PYRAZOLYL GUANIDINE F1F0-ATPASE INHIBITORS AND THERAPEUTIC USES THEREOF |
摘要 |
The invention provides trifluoromethyl pyrazolyl guanidine compounds that inhibit F1F0-ATPase, and methods of using trifluoromethyl pyrazolyl guanidine compounds as therapeutic agents to treat medical disorders, such as an immune disorder, inflammatory condition, or cancer. |
申请公布号 |
US2015183745(A1) |
申请公布日期 |
2015.07.02 |
申请号 |
US201414565463 |
申请日期 |
2014.12.10 |
申请人 |
Lycera Corporation |
发明人 |
Hurd Alexander R.;Taylor Clarke B.;Wang Jian;Zhou Peng |
分类号 |
C07D231/38 |
主分类号 |
C07D231/38 |
代理机构 |
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代理人 |
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主权项 |
1. A compound represented by Formula I: or a geometric isomer or tautomer; or a pharmaceutically acceptable salt or solvate of any of the foregoing; wherein R1 is a chloro group located at either the meta-position or para-position of the phenyl group to which it is attached. |
地址 |
Ann Arbor MI US |