主权项 |
1. The compound of Formula I: wherein Z1 is selected from the group consisting of CR2a and N; Z2 is selected from the group consisting of CR2b and N; Z3 is selected from the group consisting of CR2 and N; with the proviso that at least 1 of Z1, Z2, or Z3 must be N; m is selected from the group consisting of 0, 1, 2, or 3; R1 is independently selected from the group consisting of chloro, fluoro, and bromo; R2a, R2b, and R2c, are independently selected from the group consisting of hydrogen, halogen, C1-C3 alkyl, fluorinated C1-C3 alkyl, cyano, C1-C3 alkoxy, and N(CH3)2; X is selected from the group consisting of n is selected from 0, 1, and 2; R3 is independently selected from the group consisting of halogen, C1-C3 alkyl, fluorinated C1-C3 alkyl, cyano, C1-C3 alkoxy, and NR4R4′ where R4 and R4′ are independently selected from the group consisting of C1-C3 alkyl, or R4 when taken together with R4′ form a ring with 3 to 6 members; A is selected from the group consisting of or a pharmaceutically acceptable salt, stereoisomer, or N-oxide thereof. |