NOVEL ANTI-TRANSFERRIN RECEPTOR ANTIBODY THAT PASSES THROUGH BLOOD-BRAIN BARRIER

摘要

Provided are a novel anti-transferrin receptor antibody that can pass through the blood-brain barrier, a fusion protein of the antibody and a protein that is administered into the blood and facilitates function in the central nervous system, and a production method for both. The fusion protein contains: an anti-human-transferrin receptor antibody that recognizes any amino acid sequence selected from a group comprising of SEQ ID 1, 2, and 3; and an amino acid sequence of another protein that is bonded to the amino acid sequence and the C-terminus side of the antibody.