发明名称 |
COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING CANCER |
摘要 |
Isolated antibodies that specifically binds to an extracellular conserved ligand binding region of a human Notch receptor and inhibits growth of a tumor are described. Also described are methods of treating cancer, the method comprising administering an anti-Notch antibody in an amount effective to inhibit tumor growth. |
申请公布号 |
US2015183878(A1) |
申请公布日期 |
2015.07.02 |
申请号 |
US201414550703 |
申请日期 |
2014.11.21 |
申请人 |
OncoMed Pharmaceuticals, Inc. |
发明人 |
GURNEY Austin;Sato Aaron Ken;Fitch-Bruhns Maureen |
分类号 |
C07K16/28 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
Redwood City CA US |