发明名称 |
ESOPHAGEAL CANCER MARKER AND USE THEREOF |
摘要 |
The present invention relates to an esophageal cancer marker and application thereof. The present invention relates to: a marker that includes Glypican-1 or an expression product thereof, or a fragment or derivative thereof, and serves to identify esophageal cancer; a detection agent that includes a substance that binds to Glypican-1 or an expression product thereof; and a composition that includes a Glypican-1 inhibitor and serves to prevent or treat esophageal cancer. Herein, Glypican-1 can be SEQ ID NO: 1 (nucleic acid sequence) or SEQ ID NO: 2 (amino acid sequence), or an equivalent thereof. |
申请公布号 |
WO2015098112(A1) |
申请公布日期 |
2015.07.02 |
申请号 |
WO2014JP06455 |
申请日期 |
2014.12.25 |
申请人 |
NATIONAL INSTITUTE OF BIOMEDICAL INNOVATION |
发明人 |
NAKA, TETSUJI;SERADA, SATOSHI;FUJIMOTO, MINORU;TOYOURA, MASAYOSHI;SHOYA, YUJI |
分类号 |
A61K39/395;A61K31/713;A61K45/00;A61K48/00;A61P1/04;A61P35/00;C07K16/18;C12N15/09;C12Q1/68;G01N33/574 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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