METHOD TO GENERATE DATA ACQUISITION METHOD OF MASS SPECTROMETRY

摘要

A process for automatically creating a measurement method suitable for plasma ion source mass spectrometry, including: semi-quantitatively measuring all elements in the sample that affect the measurement; determining a plasma condition based on the total concentration of the semi-quantitatively measured elements; for each of the semi-quantitatively measured elements, estimating signal strengths of the element and an interference component in the sample to be measured and based on the resultant estimates, estimating the concentration of the element; and, based on the estimated signal strengths of the elements and the interference components and the estimated concentrations of the elements, creating at least one mass spectrometry method including at least one of: (1) a plasma condition; (2) an internal standard to be added to the sample; (3) a tuning condition for the collision/reaction cell; (4) a mass-to-charge ratio used in the mass spectrometer; and (5) an integration time used in the mass spectrometer.

主权项

1. In a plasma ion source mass spectrometry apparatus wherein a sample to be measured is supplied into plasma to ionize elements in the sample, a beam of the generated ions is introduced into a mass spectrometer through a collision/reaction cell, and ionized elements are separated and detected according to mass-to-charge ratio, a process for automatically creating a mass spectrometry method, the process comprising the steps of:
semi-quantitatively measuring at least all elements in the sample that affect the setting of measurement conditions; determining a plasma condition based on the total concentration of the semi-quantitatively measured elements; for each of the semi-quantitatively measured elements, estimating signal strengths of the element and interference components in the sample and, based on the resultant estimates, estimating the concentration of the element; and based on the estimated signal strengths of the elements and the interference components and the estimated concentrations of the elements, creating at least one mass spectrometry method including at least one of: (1) a plasma condition; (2) a combination of internal standard elements used for correction at the time of quantitating an element to be measured; (3) a turning condition for the collision/reaction cell; (4) a mass-to-charge ratio used in a mass spectrometer; and (5) an integration time used in the mass spectrometer.