发明名称 |
COMPOUND AND USE OF COMPOUND TO PREPARE A RADIOLABELLED COMPOUND |
摘要 |
The invention is directed to a compound according to formula (1) wherein R2 is fluorine, X is nitrogen or carbon and R3 is an organic group. The invention is also directed to the use of this compound as a precursor for the preparation of a 11C or 18F-radio labelled compound. The radio labelled compound may be used in an in vivo diagnostic or imaging method. |
申请公布号 |
US2015183743(A1) |
申请公布日期 |
2015.07.02 |
申请号 |
US201314412329 |
申请日期 |
2013.07.04 |
申请人 |
STICHTING VU-VUMC |
发明人 |
Christiaans Johannes Antonius Maria;Windhorst Albert Dirk;Metaxas Athanasios;Klein Pieter Jacob;Kooijman Esther Johanna Maria;Van Berckel Bart Nicolaas Maria |
分类号 |
C07D213/74 |
主分类号 |
C07D213/74 |
代理机构 |
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代理人 |
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主权项 |
1. A compound having the structure of formula I or formula II:wherein R1 is a hydrogen, or an optionally fluorinated alkoxy group having 1 to 5 carbon atoms, R2 is fluorine, R5 is selected from a hydroxyl, a hydrogen or an optionally fluorinated alkoxy group having 1 to 5 carbon atoms, X is nitrogen or carbon and R3 is an organic group, or salts or solvates thereof. |
地址 |
Amsterdam NL |