发明名称 COMPOUND AND USE OF COMPOUND TO PREPARE A RADIOLABELLED COMPOUND
摘要 The invention is directed to a compound according to formula (1) wherein R2 is fluorine, X is nitrogen or carbon and R3 is an organic group. The invention is also directed to the use of this compound as a precursor for the preparation of a 11C or 18F-radio labelled compound. The radio labelled compound may be used in an in vivo diagnostic or imaging method.
申请公布号 US2015183743(A1) 申请公布日期 2015.07.02
申请号 US201314412329 申请日期 2013.07.04
申请人 STICHTING VU-VUMC 发明人 Christiaans Johannes Antonius Maria;Windhorst Albert Dirk;Metaxas Athanasios;Klein Pieter Jacob;Kooijman Esther Johanna Maria;Van Berckel Bart Nicolaas Maria
分类号 C07D213/74 主分类号 C07D213/74
代理机构 代理人
主权项 1. A compound having the structure of formula I or formula II:wherein R1 is a hydrogen, or an optionally fluorinated alkoxy group having 1 to 5 carbon atoms, R2 is fluorine, R5 is selected from a hydroxyl, a hydrogen or an optionally fluorinated alkoxy group having 1 to 5 carbon atoms, X is nitrogen or carbon and R3 is an organic group, or salts or solvates thereof.
地址 Amsterdam NL