摘要 |
PROBLEM TO BE SOLVED: To provide a novel compound capable of modulating the G-protein-coupled receptor GPR40, a composition comprising the compound, and a method for using the compound.SOLUTION: There is provided a compound of the formula in the figure or a salt thereof. (Arepresents substituted or unsubstituted aryl or heteroaryl; X represents C(HR5); R1 represents H or alkyl; Rrepresents H, substituted or unsubstituted alkyl, alkoxy, halo, alkynyloxy, aryloxy, heteroaryloxy, aryl, or heteroaryl; and Rrepresents H, substituted or unsubstituted alkyl, alkoxy, or halo; and Rrepresents H, substituted or unsubstituted alkyl; where Rmay be connected as shown by the dotted line in the figure.) |