The presently disclosed subject matter provides antibodies that bind KLB and FGFR1, and methods of using the same. In certain embodiments, an antibody of the present disclosure includes a bispecific antibody that binds to an epitope present on FGFR1 and binds to an epitope present on KLB.
申请公布号
WO2015100366(A1)
申请公布日期
2015.07.02
申请号
WO2014US72245
申请日期
2014.12.23
申请人
GENENTECH, INC.;F. HOFFMANN-LA ROCHE AG
发明人
CHEN, YONGMEI;ERNST, JAMES;KIM, HOK SEON;SONODA, JUNICHIRO;SPIESS, CHRISTOPH;STAWICKI, SCOTT;WU, YAN