发明名称 METHODS OF TREATMENT AND PREVENTION OF NEURODEGENERATIVE DISEASES AND DISORDERS
摘要 The present invention provides compostions and methods useful for treating and preventing neurodenerative disease and neurologically related disorders by inhibition of Lp-PLA2. The compositions and methods are useful for treating and preventing diseases and disorders with abnormal blood brain barrier (BBB) function, for example neurodegenerative diseases with a permeable BBB, such as but not limited to, Alzhiemer's Disease, Huntington's Disease, Parkinson's Disease and Vascular Dementia.
申请公布号 US2015183748(A1) 申请公布日期 2015.07.02
申请号 US201414561355 申请日期 2014.12.05
申请人 Thomas Jefferson University ;Rowan University 发明人 SHI Yi;NAGELE Robert
分类号 C07D239/38 主分类号 C07D239/38
代理机构 代理人
主权项 1. (canceled)
地址 Philadelphia PA US