发明名称 |
IMMUNOCOMPROMISED UNGULATES |
摘要 |
Porcine animals, tissue and organs as well as cells and cell lines derived from such animals are provided that lack functional endogenous immunoglobulin loci and are deficient in immunoglobulin expression and B-cells. These animals are useful as model systems for research and for development of new pharmaceutical and biological agents. In addition, methods are provided to prepare such animals. |
申请公布号 |
EP2348827(B1) |
申请公布日期 |
2015.07.01 |
申请号 |
EP20090824080 |
申请日期 |
2009.10.27 |
申请人 |
REVIVICOR, INC. |
发明人 |
AYARES, DAVID, L.;MENDICINO, MICHAEL;WELLS, KEVIN;DANDRO, AMY, S. |
分类号 |
A01K67/027;C07K14/705;C12N15/85;G01N33/50;G01N33/53 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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