发明名称 |
BORON CLUSTER-MODIFIED PEG LIPID DERIVATIVE, AND MOLECULAR ASSEMBLY USING SAME |
摘要 |
The present invention provides a novel boron carrier compound that can be used for boron neutron capture therapy for cancer, and that can realize improvement in the efficiency of a Drug Delivery System (DDS) and an increase in the boron concentration in a tumor. The present invention provides a boron cluster-modified PEG lipid derivative represented by Formula (I):
wherein, m and n are each independently an integer of 1-4, q is an integer of 1-280, and R 1 and R 2 are each independently a hydrocarbon group with a carbon number of 8-22, and a molecular assembly containing the same. |
申请公布号 |
EP2889302(A1) |
申请公布日期 |
2015.07.01 |
申请号 |
EP20130831030 |
申请日期 |
2013.08.22 |
申请人 |
UNIVERSITY OF TSUKUBA |
发明人 |
MATSUMURA, AKIRA;NAKAI, KEI;SHIRAKAWA, MAKOTO |
分类号 |
A61K41/00;A61K9/127;A61K31/69;A61K47/24;A61K47/28;A61K47/34;C07F5/05;C07F9/09;C07F19/00;C08G65/328 |
主分类号 |
A61K41/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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