发明名称 |
METHOD FOR PRODUCING ARYL AND HETEROARYLACETIC ACID DERIVATIVES |
摘要 |
<p>The present invention relates to a process for preparing alpha-arylmethylcarbonyl compound of the formula (III), characterized in that aryl- and heteroarylacetic acids and derivatives thereof of the formula (I) are reacted with alpha-halomethylcarbonyl compounds of the formula (II) in the presence of a palladium catalyst, of a phosphine ligand, of an inorganic base and of a phase transfer catalyst, optionally using an organic solvent.</p> |
申请公布号 |
EP2526081(B1) |
申请公布日期 |
2015.07.01 |
申请号 |
EP20110700418 |
申请日期 |
2011.01.14 |
申请人 |
BAYER INTELLECTUAL PROPERTY GMBH |
发明人 |
HIMMLER, THOMAS;GOOSSEN, LUKAS, J.;ZIMMERMANN, BETTINA |
分类号 |
C07D295/192;C07C45/68;C07C67/343;C07C69/612;C07C69/616;C07C69/734;C07C69/738;C07C69/76 |
主分类号 |
C07D295/192 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|