发明名称 |
STREPTOCOCCUS BACTERIOPHAGE LYSINS FOR DETECTION AND TREATMENT OF GRAM POSITIVE BACTERIA |
摘要 |
The present invention provides methods, compositions and articles of manufacture useful for the prophylactic and therapeutic amelioration and treatment of gram-positive bacteria, including Streptococcus and Staphylococcus, and related conditions. The invention provides compositions and methods incorporating and utilizing Streptococcus suis derived bacteriophage lysins, particularly PlySs2 and/or PlySs1 lytic enzymes and variants thereof, including truncations thereof. Methods for treatment of humans are provided. |
申请公布号 |
EP2699253(A4) |
申请公布日期 |
2015.07.01 |
申请号 |
EP20120773653 |
申请日期 |
2012.04.20 |
申请人 |
THE ROCKEFELLER UNIVERSITY |
发明人 |
FISCHETTI, VINCENT, A.;SCHMITZ, JONATHAN;GILMER, DANIEL;EULER, CHAD |
分类号 |
A61K38/16;A61P31/04 |
主分类号 |
A61K38/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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