摘要 |
<p>Three processes are disclosed for making 1,1,1,4,4,4-hexafluoro-2-butene. The first process involves reacting 2,2-dichloro-1,1,1-trifluoroethane with copper in the presence of an amide solvent and 2,2'-bipyridine. The second process involves reacting 2,2-dichloro-1,1,1-trifluoroethane with copper in the presence of an amide solvent and a Cu(I) salt. The third process involves reacting 2,2-dichloro-1,1,1-trifluoroethane with copper in the presence of an amide solvent, 2,2'-bipyridine and a Cu(I) salt.</p> |