Dental bleaching compositions having long-term rheological stability and devices, kits and methods that utilize such compositions

摘要

Dental bleaching compositions include a dental bleaching agent, a generally linear high molecular weight (i.e., greater than about 500,000) polyvinyl pyrrolidone (PVP) and/or polyethylene oxide (PEO) tissue adhesion agent included in amount that imparts a high level of adhesiveness, a rheology-modifying agent such as fumed silica or fumed alumina that reduces or eliminates stringiness otherwise caused by the high molecular weight PVP and/or PEO, and a solvent or carrier. Dental bleaching compositions may include carboxypolymethylene instead of or in addition to PVP and/or PEO, wherein the fumed silica or fumed alumina increases long-term rheological stability even in the presence of a high concentration of dental bleaching agent. Dental treatment devices including a barrier layer and a quantity of the dental bleaching composition positioned adjacent to the barrier layer.

主权项

1. A dental bleaching composition for use in bleaching a person's teeth having improved adhesiveness and reduced stringiness, comprising:
a peroxide dental bleaching agent included in amount so as to provide a minimum of about 5% by weight hydrogen peroxide; a tissue adhesion agent, said tissue adhesion agent comprising at least one of:
polyvinyl pyrrolidone (PVP) and/or polyethylene oxide (PEO) having a molecular weight of at least 500,000 and included in a minimum amount of about 5% by weight; orcarboxypolymethylene included in a minimum amount of about 3% by weight; a rheology-modifying agent comprising a finely divided inorganic particulate that is stable in the presence of the dental bleaching agent and included in an amount in a range of about 1% to about 8.5% so as to increase long-term rheological stability over time compared to a composition comprising the tissue adhesion agent in the presence of the peroxide dental bleaching agent and in the absence of the rheology-modifying agent; and an aqueous liquid carrier that includes water and polyol into which the dental bleaching agent, tissue adhesion agent, and rheology-modifying agent are dispersed, wherein the tissue adhesion agent, the polyol, and the rheology-modifying agent have a combined concentration that exceeds the concentration of the water so that the dental bleaching composition has long-term rheological stability and retains the consistency of a sticky and adhesive gel for a period of at least 3 months.