发明名称 |
Method for treating and diagnosing cancer by using cell-derived microvesicles |
摘要 |
Disclosed is a method for the treatment and/or diagnosis of cancer, using bacterial cell-derived microvesicles, which is highly effective in cancer therapy with a significant reduction in side effects. Also, a method is provided for delivering of a drug therapeutic or diagnostic for a disease, using bacterial cell-derived microvesicles loaded with the drug, thereby treating and diagnosing the disease effectively and specifically. |
申请公布号 |
US9066971(B2) |
申请公布日期 |
2015.06.30 |
申请号 |
US201113807843 |
申请日期 |
2011.06.30 |
申请人 |
POSTECH ACADEMY-INDUSTRY FOUNDATION |
发明人 |
Gho Yong Song;Kim Oh Youn;Jang Su Chul;Yoon Chang Min;Kim Yoon Keun |
分类号 |
A61K35/74;A61K9/50;A61K47/46;A61K49/00;A61K47/48;A61K31/616;A61K31/704;A61K38/12;A61K38/16;A61K39/00 |
主分类号 |
A61K35/74 |
代理机构 |
Lucas & Mercanti, LLP |
代理人 |
Lucas & Mercanti, LLP |
主权项 |
1. A method of treating cancer in a subject in need thereof, said method comprising administering bacterial cell-derived microvesicles to said subject,
wherein the bacterial cell-derived microvesicles are derived from a Gram-positive bacteria that is genetically transformed to have a reduced toxicity; and wherein the cancer is treated. |
地址 |
Gyeongsangbuk-do KR |