发明名称 |
METHODS AND COMPOSITIONS FOR CCR-5 GENE INACTIVATION |
摘要 |
Disclosed herein are methods and compositions for inactivating CCR-5 genes, using zinc finger nucleases (ZFNs) comprising a zinc finger protein and a cleavage domain or cleavage half-domain. Polynucleotides encoding ZFNs, vectors comprising polynucleotides encoding ZFNs, such as adenovirus (Ad) vectors, and cells comprising polynucleotides encoding ZFNs and/or cells comprising ZFNs are also provided. |
申请公布号 |
CA2651499(C) |
申请公布日期 |
2015.06.30 |
申请号 |
CA20072651499 |
申请日期 |
2007.05.23 |
申请人 |
SANGAMO BIOSCIENCES, INC. |
发明人 |
ANDO, DALE;HOLMES, MICHAEL CHRISTOPHER;LEE, GARY KA LEONG |
分类号 |
C07K14/47;C12N15/62;C12N15/63 |
主分类号 |
C07K14/47 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|