发明名称 |
High concentration antibody-containing liquid formulation and a method for inhibiting dimerization of molecules of an antibody in a liquid formulation |
摘要 |
<p>The problem to be solved is to provide an antibody-containing formulation which is stable and suited for subcutaneous administration, wherein dimerization and deamidation is prevented during long-term storage. The present application is directed to a stable antibody-containing liquid formulation characterized by containing arginine and methionine.</p> |
申请公布号 |
IL206548(A) |
申请公布日期 |
2015.06.30 |
申请号 |
IL20100206548 |
申请日期 |
2010.06.22 |
申请人 |
F. HOFFMANN-LA ROCHE AG;CHUGAI SEIYAKU KABUSHIKI KAISHA;TOSHIYUKI MORICHIKA;DAISUKE KAMEOKA;YOSHIMI IMAEDA;TERUTOSHI MAEDA;OLIVER BORIS STAUCH |
发明人 |
TOSHIYUKI MORICHIKA;DAISUKE KAMEOKA;YOSHIMI IMAEDA;TERUTOSHI MAEDA;OLIVER BORIS STAUCH |
分类号 |
A61K |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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