| 发明名称 | Hybrid SCFA-hydroxyl-derivatized monosaccharides, methods of synthesis, and methods of treating disorders | ||
| 摘要 | Described herein are fatty acid carbohydrate-hydroxyl-hybrid compounds and derivatives thereof, and methods of treating or preventing disease and disease symptoms using the compounds and compositions thereof. | ||
| 申请公布号 | US9067960(B2) | 申请公布日期 | 2015.06.30 |
| 申请号 | US201414246809 | 申请日期 | 2014.04.07 |
| 申请人 | The Johns Hopkins University | 发明人 | Yarema Kevin J.;Aich Udayanath;Campbell Christopher T.;Sampathkumar Srinivasa-Gopalan;Choi Sean S.;Meledeo Michael A.;Weier Christopher |
| 分类号 | C07H13/04;C07H15/04;C07H23/00;C07H5/06;C07H7/027 | 主分类号 | C07H13/04 |
| 代理机构 | Mintz Levin Cohn Ferris Glovsky and Popeo, P.C. | 代理人 | Mintz Levin Cohn Ferris Glovsky and Popeo, P.C. ;Corless Peter F.;Cowles Christopher R. |
| 主权项 | 1. A compound of formula I, or pharmaceutically acceptable salt thereof:wherein, R4 is H and each of R1, R2 and R3 is —C(O)(CH2)2CH3; and R is alkyl, alkenyl or alkyne, each of which is optionally substituted with 1-4 substituents selected from acyl, oxo, azido, aryl, halogen, —OC(O)alkyl, or —SC(O)alkyl. | ||
| 地址 | Baltimore MA US | ||