The invention provides human engineered DKK-1 antibodies or antigen-binding fragments thereof, that bind to, and inhibit the activity of, human DKK-1, and which are effective in treating diseases in which pathogenesis is mediated by DKK-1.
申请公布号
EA021401(B1)
申请公布日期
2015.06.30
申请号
EA20110071237
申请日期
2010.04.06
申请人
ELI LILLY AND COMPANY
发明人
CHEDID MARCIO;DARLING RYAN, JAMES;GALVIN RACHELLE, JEANETTE;SWANSON BARBARA, ANNE