发明名称 |
Componente para uma vacina contra malária, vacina para malária, processo para a preparação do componente, uso do componente, e, método de tratar um paciente suscetível às infecções por plasmodium |
摘要 |
<p>The present invention relates to a component for a malaria vaccine comprising: a) an immunogenic particle RTS, S and/or b) an immunogenic particle derived from the CS protein of one or more P. vivax strains and S antigen from Hepatitis B and optionally unfused S antigen, or c) an immunogenic particle comprising RTS, CSV-S and optionally unfused S antigen, and d) a stabilizing agent comprising a stabilizing agent with at least one thiol functional group, or mixtures thereof. Methods for preparing the component, its use in medicine, particularly in the prevention of malarial infections, compositions/vaccines containing the component and use of the latter, particularly in therapy are also disclosed.</p> |
申请公布号 |
BRPI0822098(A2) |
申请公布日期 |
2015.06.30 |
申请号 |
BR2008PI22098 |
申请日期 |
2008.12.18 |
申请人 |
GLAXOSMITHKLINE BIOLOGICALS S.A. |
发明人 |
DOMINIQUE INGRID LEMOINE;FLORENCE EMILIE JEANNE FRANCOISE WAUTERS |
分类号 |
A61K39/015;A61K39/39;A61K47/18 |
主分类号 |
A61K39/015 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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