发明名称 Ingenol-3-acylates iii and ingenol-3-carbamates
摘要 <p>The invention relates to compounds of general formula I wherein R is heteroaryl optionally substituted by R7; or R is heterocycloalkyl or heterocycloalkenyl, optionally substituted by R8; or R is X wherein X is—NR11R12; and pharmaceutically acceptable salts, hydrates, or solvates thereof, for use—alone or in combination with one or more other pharmaceutically active compounds—in therapy, for preventing, treating or ameliorating diseases or conditions responsive to stimulation of neutrophil oxidative burst, responsive to stimulation of keratinocyte IL-8 release or responsive to induction of necrosis.</p>
申请公布号 IL238396(D0) 申请公布日期 2015.06.30
申请号 IL20150238396 申请日期 2015.04.21
申请人 LEO LABORATORIES LIMITED 发明人
分类号 C07C 主分类号 C07C
代理机构 代理人
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