DEVELOPMENT OF LONG ACTING AND CELL PERMEABLE BETA-DEFENSIN 3 AND -3H BY CONJUGATING LAURIC ACID AND CELL PERMEABLE PEPTIDE RESPECTIVELY AND COSMETIC COMPOSTION COMPRISING THE SAME

摘要

The present invention relates to a long-acting derivatives through fusion of antimicrobial peptide beta-defensin 3 and laulic acid, development of skin permeation type derivatives through fusion of cell permeation type peptite, and cosmetic composition containing the same. More specifically, the present invention relates to antimicrobial peptide beta-defensin 3 and laulic acid, new cell permeation type peptite, and cosmetic composition containing the same. The beta-defensin 3 and 3H (homolog) peptite derivative combined with laulic acid has an antimicrobial property and has a function of curing atopy dermatitis and acne, thereby, being used as various skin improvement cosmetics, and medicines.