发明名称 |
Nye screeningsstrategier til identifikation af antistoffer eller fragmenter deraf, som binder et antigen med enzymatisk aktivitet |
摘要 |
<p>The present invention discloses novel screening strategies for the identification of binders that target the active site of enzymatic antigens. The present invention also discloses antigen-binding moieties which bind to the NS2B-NS3 Proteinase of West Nile Virus, in particular binders which bind to the active site, thereby inhibiting the enzymatic activity of the proteinase. The antigen-binding moieties of the present invention have numerous therapeutic and diagnostic applications.</p> |
申请公布号 |
DK2464657(T3) |
申请公布日期 |
2015.06.29 |
申请号 |
DK20100741944T |
申请日期 |
2010.08.06 |
申请人 |
MORPHOSYS AG |
发明人 |
FRISCH, CHRISTIAN;KNAPPIK, ACHIM;STRONGIN, ALEX, Y;SHIRYAEV, SERGEY, A |
分类号 |
C07K16/40;C07K14/005;C07K16/10;C12Q1/37 |
主分类号 |
C07K16/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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