摘要 |
Disclosed herein is a container device for receiving blood in a reservoir and controlling coagulation in a blood sample, wherein the a reservoir comprises thrombin and coagulation controlling agent selected from citrate, isocitrate, a protamine salt, benzamidine, or para-aminobenzamidine. Additives such as water soluble polymers and sugars are also contemplated. The method combines thrombin and a coagulation controlling agent to stabilize thrombin or accelerate its activity in a blood sample. |