发明名称 |
PYRAZOLOPYRIMIDINE JAK INHIBITOR COMPOUNDS AND METHODS JAK |
摘要 |
The invention provides JAK kinase inhibitors of Formula Ia, enantiomers, diasteriomers or pharmaceutically acceptable salts thereof, wherein R 1 , R 2 , R 7 and Z are defined herein, a pharmaceutical composition that includes a compound of Formula Ia and a pharmaceutically acceptable carrier, adjuvant or vehicle, and methods of treating or lessening the severity of a disease or condition responsive to the inhibition of a JAK kinase activity in a patient. |
申请公布号 |
HK1161529(A1) |
申请公布日期 |
2015.06.26 |
申请号 |
HK20120101703 |
申请日期 |
2012.02.21 |
申请人 |
GENENTECH INC. |
发明人 |
BLANEY, JEFFREY;GIBBONS, PAUL A.;HANAN, EMILY;LYSSIKATOS, JOSEPH P.;MAGNUSON, STEVEN R.;PASTOR, RICHARD;RAWSON, THOMAS E.;ZHOU, AIHE;ZHU, BING-YAN |
分类号 |
C07D |
主分类号 |
C07D |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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