SUBSTITUTED PIPERIDINYL-TETRAHYDROQUINOLINES AND THEIR USE AS ALPHA-2C ADRENORECEPTOR ANTAGONISTS

摘要

The invention relates to novel substituted piperidinyl-tetrahydroquinolines of formula (I), methods for producing same, their use for treating and/or preventing diseases, and their use in the production of medications for treating and/or preventing diseases, particularly for treating and/or preventing diabetic microangiopathies, diabetic abscesses of the extremities, particularly promoting tissue repair in diabetic foot ulcers, diabetic heart failure, diabetic coronary microvascular heart diseases, peripheral vascular and cardiovascular diseases, thromboembolic diseases and ischaemia, peripheral circulatory disorders, Raynaud's phenomenon, CREST syndrome, microcirculatory disorders, intermittent claudication, and peripheral and autonomic neuropathies.