发明名称 GAMMA-AMINOBUTYRIC ACID (GABA) ANALOGUES FOR THE TREATMENT OF PAIN AND OTHER DISORDERS
摘要 A compound of Formula (1) wherein R1 represents hydrogen, halo, a C1-C4 alkyl group, a C1-C4 alkylhalide group, a C1-C4 alkoxy-C2-C4 alkyl group, a C2-C4 alkenyl group, a C2-C4 alkynyl group or a C3- C7 cyclo alkyl group; R2 represents Formula (1)' or Formula (1)'' a tautomer thereof; and R3 represents hydrogen, a C1-C4 alkyl group, a C1-C4 alkoxy-C2-C4 alkyl group or a C7 cyclo alkyl group; or a pharmaceutically acceptable salt or solvate thereof. Processes to prepare said compounds and novel intermediates are also claimed. Such compound finds utility in treating neuropathic pain and disorders of the central nervous system.
申请公布号 CA2932050(A1) 申请公布日期 2015.06.25
申请号 CA20142932050 申请日期 2014.12.16
申请人 NOVASSAY SA 发明人 MEGHANI, PREMJI;KRICEK, FRANZ
分类号 C07D257/04;A61K31/4245;A61P25/02;A61P25/04;A61P25/06;A61P25/08;A61P25/16;A61P25/18;A61P25/22;A61P25/28;C07C205/02;C07C255/07;C07D271/07 主分类号 C07D257/04
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