| 发明名称 |
FLAVANOID COMPOUNDS AND PROCESS FOR PREPARATION THEREOF |
| 摘要 |
The present invention relates to flavanoid compounds of general formula (X1) wherein: R1 is selected from a group consisting of morpholinyl, N-methyl piperizinyl, piperidinyl and N,N′-dimethylamino groups, and n ranges from 3 to 6, and process for preparation thereof. The present invention relates to the demonstration of anti Helicobacter pylori activity and gastric antisecretory activity of semisynthetically designed flavonoid compounds, to be used for the prevention and treatment of gastroduodenal disorders in general and peptic ulcer diseases in particular. The present invention also relates to a hetero-dimeric bi-functional molecule that can be used as monotherapy substituting/replacing/overcoming currently used triple/quadruple therapy, thereby implicating/anticipating/envisaging its commercial applicability. |
| 申请公布号 |
US2015174135(A1) |
申请公布日期 |
2015.06.25 |
| 申请号 |
US201514634665 |
申请日期 |
2015.02.27 |
| 申请人 |
Council of Scientific & Industrial Research |
发明人 |
DAS Pratap Kumar;GOSWAMI Suchandra;CHINNIAH Annalakshmi;RAO Janaswamy Madhusudana;KATRAGADDA Suresh Babu |
| 分类号 |
A61K31/5377;A61K31/496;A61K31/453 |
主分类号 |
A61K31/5377 |
| 代理机构 |
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代理人 |
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| 主权项 |
1. A flavanoid compound of general formula X1,wherein R1 is selected from a group consisting of morpholinyl, N-methyl piperizinyl, piperidinyl and N,N′-dimethylamino groups, wherein n ranges from 3 to 6, or a pharmaceutically acceptable salt thereof, for treating or preventing Helicobacter pylori infection and gastric hypersecretion. |
| 地址 |
New Delhi IN |
