发明名称 |
ACTIVATABLE ANTIBODIES THAT BIND EPIDERMAL GROWTH FACTOR RECEPTOR AND METHODS OF USE THEREOF |
摘要 |
The disclosure relates generally to variant activatable antibodies that include a masking moiety (MM), a cleavable moiety (CM), and an antibody (AB) that specifically binds to epidermal growth factor receptor (EGFR), and to methods of making and using these variant anti-EGFR activatable antibodies in a variety of therapeutic, diagnostic and prophylactic indications. |
申请公布号 |
WO2015066279(A3) |
申请公布日期 |
2015.06.25 |
申请号 |
WO2014US63077 |
申请日期 |
2014.10.30 |
申请人 |
CYTOMX THERAPEUTICS, INC. |
发明人 |
LOWMAN, HENRY BERNARD;DESNOYERS, LUC ROLAND;LIU, SHOUCHUN |
分类号 |
C07K16/28 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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