| 发明名称 |
MODIFIED THERAPEUTIC AGENTS, STAPLED PEPTIDE LIPID CONJUGATES, AND COMPOSITIONS THEREOF |
| 摘要 |
Methods and compositions are provided for extending the half-life of a therapeutic agent. A modified therapeutic agent (mTA) comprises a therapeutic agent, a staple, and a half-life extending molecule. The mTAs disclosed herein may be used to treat a disease or a condition in a subject in need thereof. |
| 申请公布号 |
WO2015095406(A1) |
申请公布日期 |
2015.06.25 |
| 申请号 |
WO2014US70977 |
申请日期 |
2014.12.17 |
| 申请人 |
THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RESEARCH;THE SCRIPPS RESEARCH INSTITUTE |
发明人 |
SHEN, WEIJUN;YANG, PENGYU;ZOU, HUAFEI;SCHULTZ, PETER, G. |
| 分类号 |
A61K31/23;A61K31/20;A61K47/30;A61K47/48 |
主分类号 |
A61K31/23 |
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