发明名称 |
TAMPER RESISTANT DOSAGE FORM WITH BIMODAL RELEASE PROFILE MANUFACTURED BY CO-EXTRUSION |
摘要 |
11GRA3639-WO/JBdk Summary: The invention relates toa monolithic pharmaceutical dosage form comprising a hot melt-extruded first segment (S ) and a second segment (S 2 ); whereinthe first segment (S ) contains at least a first pharmacologically active ingredient (A ) and/or the second segment (S 2 )contains at least a second pharmacologically active ingredient (A 2 ); andthe segment (S ) and/or the segment (S 2 ) is tamper-resistantand/orexhibits a breaking strength of at least 300N. |
申请公布号 |
CA2933983(A1) |
申请公布日期 |
2015.06.25 |
申请号 |
CA20142933983 |
申请日期 |
2014.12.15 |
申请人 |
GRUNENTHAL GMBH |
发明人 |
GEIBLER, ANJA;DENKER, JANA;WENING, KLAUS;BARNSCHEID, LUTZ |
分类号 |
A61K31/137;A61K9/16;A61K9/20;A61K31/167 |
主分类号 |
A61K31/137 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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