| 摘要 |
The use of chemically modified proteins as enteric or gastroresistant coatings for oral dosage forms containing an active ingredient is described. Typical enteric coatings are made from synthetic polymers and function by acting as a barrier to gastric medium penetration. In some cases, the manufacture of such coatings requires the use of hazardous chemicals and the safety of some of the synthetic polymers that have been used in enteric coatings have been questioned. Protein-based enteric coatings of the present description present a more natural alternative to enteric coatings produced from synthetic polymers to provide gastroresistance to oral dosage forms. Protein-based film-forming solutions and uses thereof in coating oral dosage forms are also provided. |
