发明名称 IMAGING AND THERAPEUTIC METHODS FOR TREATING PARATHYROID TUMORS
摘要 It has been discovered that human parathyroid tumor cells express high densities of folate receptors which could provide a target that may be used for localization. In certain embodiments, the disclosure relates to methods of detecting and imaging parathyroid tumors or canccrous cells in tissues using a folatc conjugate to enhance imaging techniques such as magnetic resonance imaging, positron emission tomography, computed tomography (CT), and single-photon emission computed tomography (SPECT). An image of radioactivities or nuclear magnetic resonance frequencies as a function of location for parcels (voxels), may be constructed and plotted. The image shows the tissues in which the tracer has become concentrated.
申请公布号 US2015174273(A1) 申请公布日期 2015.06.25
申请号 US201314416694 申请日期 2013.07.24
申请人 EMORY UNIVERSITY 发明人 Weber Collin J.
分类号 A61K51/04 主分类号 A61K51/04
代理机构 代理人
主权项 1. A method comprising a) administering a metal particle-folate-conjugate to a subject at risk of, suspected of, or diagnosed with a parathyroid tumor; b) exposing an area suspected of containing the parathyroid tumor of the subject to a magnetic field and a radio frequency pulse; and c) detecting nuclear resonance frequencies in the area.
地址 Atlanta GA US