| 发明名称 |
COMPOUNDS FOR TARGETED IMMUNOTHERAPY |
| 摘要 |
Compounds for targeted immunotherapy, compositions comprising the compounds and use of the compounds in the treatment of diseases such as cancer are disclosed. The compounds having the structure of formula TM-Ln-AM, wherein TM is a targeting moiety, AM is an activating moiety that is capable of activating a human dendritic cell, NK cell, or tumor cell, or a combination thereof, Ln is a linker, and n is an integer selected from 0 and 1. |
| 申请公布号 |
US2015174268(A1) |
申请公布日期 |
2015.06.25 |
| 申请号 |
US201314408268 |
申请日期 |
2013.07.16 |
| 申请人 |
Shanghai Birdie Biotech, Inc. |
发明人 |
Li Lixin |
| 分类号 |
A61K47/48;A61K31/4745;A61K45/06 |
主分类号 |
A61K47/48 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A compound having the structure of Formula (I):
TM-Ln-AM (I),wherein TM is a targeting moiety, AM is an activating moiety that is capable of activating a human dendritic cell, NK cell, macrophage, or tumor cell, or a combination thereof, Ln is a linker, and n is an integer selected from 0 and 1,
with the proviso that when TM comprises an antibody, AM does not comprise a CpG oligonucleotide. |
| 地址 |
Beijing CN |
