| 发明名称 |
VACCINE |
| 摘要 |
The present invention relates to novel combinations of active agents and methods for treatment of retrovirus infections including HIV infections and AIDS. In particular, the present invention relates to novel use of administrations and combinations of a compound to stimulate the humoral immunity and/or peptides that elicit a cell-mediated immune response in a subject; and immunomodulatory compounds and/or a reservoir purging agent, such as a histone deacetylase (HDAC) inhibitor. |
| 申请公布号 |
US2015174235(A1) |
申请公布日期 |
2015.06.25 |
| 申请号 |
US201314405093 |
申请日期 |
2013.06.06 |
| 申请人 |
Bionor Immuno AS |
发明人 |
Hoie Lars;Lundemose Anker;Okvist Mats;Hovden Arnt Ove;Gronvold Maja Sommerfelt;Hansen Vidar Wendel;Sorensen Birger |
| 分类号 |
A61K39/21;A61K45/06;A61K31/454 |
主分类号 |
A61K39/21 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for treating a human retrovirus infection, such as immunodeficiency virus I (HIV) in a human infected with such virus, such as HIV, the method comprising administering separately, sequentially in any order or simultaneously (1) one or more peptides that elicit a cell-mediated immune response in a subject and/or a compound to stimulate the humoral immunity in a subject; and (2) a reservoir purging agent, such as a histone deacetylase (HDAC) inhibitor, and/or an immunomodulatory compound. |
| 地址 |
Skien NO |
