发明名称 |
METHOD OF PURIFYING/CONCENTRATING SUGAR CHAINS WITH A SUGAR CHAIN-TRAPPING MOLECULE AND METHOD OF ANALYZING SUGAR CHAIN STRUCTURE |
摘要 |
The present invention provides substance which can specifically interact with sugar chains. Further, the present invention provides a method for separating, concentrating, or purifying sugar chains or a sugar chain-containing substance in a sample, comprising the steps of: a) contacting a sugar chain-trapping carrier comprising a substance which can specifically interact with sugar chains with the sample in a fluid phase under conditions that the sugar chain-trapping carrier can react with the sugar chains or sugar chain-containing substance; b) isolating a composite of the sugar chain-trapping carrier and the sugar chains or sugar chain-containing substance from the fluid phase; and c) exposing the composite to the conditions that the interaction between the sugar chain-trapping carrier and the sugar chains or sugar chain-containing substance is at least partially eliminated. |
申请公布号 |
US2015175652(A1) |
申请公布日期 |
2015.06.25 |
申请号 |
US201414581585 |
申请日期 |
2014.12.23 |
申请人 |
Sumitomo Bakelite Co., Ltd. |
发明人 |
Nishimura Shinichiro;Niikura Kenichi;Nakagawa Hiroaki;Okayama Minenobu |
分类号 |
C07K1/14;C07K14/77;G01N33/53;C07H3/06;C07H1/06;G01N33/68;C07K16/00;C07K14/79 |
主分类号 |
C07K1/14 |
代理机构 |
|
代理人 |
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主权项 |
1. A method for separating, concentrating, or purifying sugar chains or a sugar chain-containing substance in a sample, comprising the steps of:
a) contacting a sugar chain-trapping carrier comprising a substance which can specifically interact with sugar chains with the sample in a fluid phase under conditions that the sugar chain-trapping carrier can react with the sugar chains or sugar chain-containing substance; b) isolating a composite of the sugar chain-trapping carrier and the sugar chains or sugar chain-containing substance from the fluid phase; and c) exposing the composite to the conditions that the interaction between the sugar chain-trapping carrier and the sugar chains or sugar chain-containing substance is at least partially eliminated. |
地址 |
Tokyo JP |