| 发明名称 |
ONE COMPONENT FIBRIN GLUE COMPRISING ZYMOGENS |
| 摘要 |
Provided herein is a single component sealant formulation (e.g. in a liquid form), methods for its preparation, and use. The formulation includes fibrinogen; vitamin K-dependent clotting zymogens comprising at least Factor II (FII) and Factor X (FX). |
| 申请公布号 |
US2015174215(A1) |
申请公布日期 |
2015.06.25 |
| 申请号 |
US201414560089 |
申请日期 |
2014.12.04 |
| 申请人 |
Omrix Biopharmaceuticals Ltd. ;Ethicon, Inc. |
发明人 |
PILPEL Yair;DEANGLIS Ashley;ZHERDEV Yuri;DORON Sivan;GORMAN Anne;NUR Israel |
| 分类号 |
A61K38/48;A61K33/14;A61K31/194;A61K31/198;A61K38/36;A61K38/17 |
主分类号 |
A61K38/48 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A sealant formulation comprising fibrinogen; vitamin K-dependent clotting zymogens comprising at least Factor II and Factor X; and at least one reversible inhibitor of at least one of the vitamin K-dependent clotting zymogens, wherein the formulation is free of an added irreversible thrombin inhibitor. |
| 地址 |
Rehovot IL |
